SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3645b222081578f77355de2621f5a1f7fb9ee2fba102bf5ca84151b72e7fd8f' 
  AND token = '4qlufgMUSIinFWtU6brvL5KB9cVIpNaIzh+g1Xpieo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}