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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4285d3edaff7f1dc0f204233cfe55fa47dddd4678b774d5fba277e1369201f5e' 
  AND token = 'ZNDbDQ9Z9Dw0HPOmbWwFkdNGqzrmY/fU3vuQ4qLvntI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}