SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b53abdb869669d3dbf6134db804655fe63121514588b1368305307850eff6ed' 
  AND token = 'F4HAIJzfTVzB7oJ/IS7yt6CFRHbBsnukBHq2qGfgLBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}