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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eab64f8d0358bed3d09ed18d0c4ab44927204d09809ea621a3283b646fbc938' 
  AND token = 'GJV34fYUiXnf/owpKk2ATDqYAbWAsd+rPGTko/Smldg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}