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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4820e20f92c9a45eccfcaeadb7c44a981a8b09fceeae7a1bc13f805d5e08059f' 
  AND token = 'Um9o6/WRY9MhIlIu7TrVHBqAVriPDnM9qBJ9bWBA5Uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}