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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9260b6225a268bc14c1f6aa728b96894aa52b7cf9874d9cec701fd2d2f7727cc' 
  AND token = 'y+TqzTdRzdrKwWHCzjWLPCASkCQmZxbJcTzQoO1uCog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}