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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a6754dae2030e1f6d672b404d7e361117a366697f24fbfcc9493c9352e9aa9f' 
  AND token = 'Y5axROGP+sACnhBbW4zD82vWt8P0WQ+bzur5HtU8U9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}