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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33097ef0fac0a250153d372d0bd7e3c91dbcf452ece7f03f28d219f87401f5e8' 
  AND token = 'vk7AG401y+VYvCzxhkiTzVRKCz6OgMzp7yVBFWSpjCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00237

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}