SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2b55c996e37f2fbf15a9d74d68f4a1aeace54a5229318f8c065495407e4f3d1' 
  AND token = 'roIkB8F9hek89TDLGCaaFpURv6pMcvM0+zSHvZgmNVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}