SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45c260672cf6f854b6e5c3c6b63b0cbafb53c47503314ebbb52eefd4621749e1' 
  AND token = 'PQ06R8b5LzgaOEsQiA3Qv7qmjddfo9U2bs5DuYbsiKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}