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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22c9b3eb3b95ac0ef6edcd821c870b19f6f2a0f08126aee031367e4f43efcce7' 
  AND token = 'kqNND00OBtp7atbrBcZyhW6/52glHycFb0TaGQZgs4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}