SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a171b259d8e5ce9e820ff0e0f862eeb08c5da513f9729cc4239c8eba23ff03ac' 
  AND token = 'zQKxddM91XjhBfqHgS9msfGPOI3vxpWAuedjjnYFRCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}