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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f0a21183ba58104961f53355fd1142d58bc65472ee50b7fe9efbff41f5ed53d' 
  AND token = 'UPTL85j94LUqIViA+wTknAYPcuJJaI+TafrH2TOQdLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00181

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}