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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ea6a8721bddf66d75fe0d1ff56650cc24d443d5dd595235ecaf1bd029c39cf' 
  AND token = 'Fil121HuzwQ+ZMt/suWTAakyfwAv//BdrHYuNrm1kDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}