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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4aae1c41dd56fd8aa32a478680c6772f0fd68c37e5a6daca930d218335d85a5' 
  AND token = 'O0AtTM0NjXVEf0MZb5hh2YtvaZkHVmX9wbuZu8mbFjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}