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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7abdc48e0c8daf91add1b08c927300879847baec721419fdf025c58cb1cb44cc' 
  AND token = '+uz6YYQu7vbsgEWMnmuEuOd2ysAqPyetOLhPCw30ev0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}