SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b41db2e79a217fd8b8912eb76e52f733ac195114a147c13a1bd7a30123012151' 
  AND token = 'QJJZXT7abQTRDTaQQ0PPMQSQFN3ROeITo19cekCS0vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}