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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '035af2cbe38a034a02cc028f90192856c217f33858cb4533ecd25e65d9bcd646' 
  AND token = 'QBxCCSbBX5S6GCuVDlUXs0qy4VezGWEWGjxDMviBanE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}