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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '309aa45964d3c36105e7c709784b0d9f261e46b2894c62e14c409a0180e04696' 
  AND token = 'mmKQptz+kccX2uJtObHGspD/6OjEuP9n/8z4Q7k0wNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}