SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65a3df94bfb42d404df8954079c43f1e593919bc40b1cdbb4cb52992b869284f' 
  AND token = 'p8D+FO7PZ9FciYfjOz3zl7I/RoofcX2TZzryaExP/SM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}