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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0e0a9337f728809aaadcc94fdb1ae9fadb5b55d29f1093b0d87e85e860c74e6' 
  AND token = '0MMNsCNL46W2NkKw8pFNUXtOvyncujoIw1ypPNbjFPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}