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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a20b3014a195c7dac393f54e22a0ca80a0382748e465c3c192bd05824123ee59' 
  AND token = 'wnc9cYYPtN44LXqK49U/KSGmFruUOFF79o1NKkrf/oQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}