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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cd0a0884fc6fb788b2708c67a2106e0e5359a5107472710ca35d3feb7280d41' 
  AND token = '1djgTCcq1BcUP7rKbkE7oCoT3jb1bcuT6Iw3iq0FVBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}