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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8e249058968e05192914aa0ed0ab370f138a660704549373331c0913c0cef48' 
  AND token = 'MD5tJ9DVS2pHZl5O0IqRKI9hHE8QEqjadrRktzsgbUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}