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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fde5bf6b55fe0209eb73104384a3f4ec50682a22a185b4723eaaf877d0e1b37a' 
  AND token = 'UIqjDzF12nYJGMAoPj7+OpsZx82b2yU1pTIuclL9ZNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}