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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50eff723580d9f1349fce00bc1b262a6a9611f59b80aaad09e5b5592b8480417' 
  AND token = 'SVuRX3po1iPc75uNIZOXeBf0joT7x7XwZKyjEl/4h/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}