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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78927d202149eee402c810b1f7753ef8d26d252c65f9a588edf87e4fcd0af0ee' 
  AND token = '99g1/vcTleonySOPkFFjgeyXQDJpqo659/bJr9Zwkqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}