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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd10c8142824a1f52703b10b59bad72ee72da80227352e35fc791bcb04f4174b0' 
  AND token = 'Jz4BMTh4rpTiu2b9Z5dWIsQxY/TZW7bNE1OTtNDSH60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}