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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbf05add443747146fe4a80e1dd1b33ae5333e52986bb93b220d3426b8c6c941' 
  AND token = '7n3e9a9FicGna8yNuonTA1aRFwfOxOJS9VhckylLF00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}