SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '402b24d4bbe22ace3b6f966a7023e71b0bf702030f4dd9d6b16ade360ecf967c' 
  AND token = 'qz9//QA/351Fqt49BYuLBw9HXW/tP7lkip5TpIGczX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}