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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b772c511114945967431a110ba16b0a97fe5337194f0c0105c093ff4b3afb64' 
  AND token = 'bp4yWsIpllywpPUX5wgBRVNCPRCMecEZDbuCWaSidOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}