SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '430e05b14425fe3a5dd300057e11781a3151f8d99f9cd3920e2b3e591425579c' 
  AND token = 'iqCiDt7hLrOMjHWfNLyvA5pYPGU0/OZwdUCWYxxsa6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}