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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dffaab779214cad65508e4866c56acc6b49978d9127bfd049d8eb5c165ce549' 
  AND token = 'focGg3r3fbrjTn8nj0a45V/1hETG1RQHCA2II0YMUbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}