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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af93f9d09d9e7f9e344fce0a052f245d480343b8e01985114e4be1feab0c861f' 
  AND token = 'L/0BNKE0xOwUB/bmT7sdT5yrtVIY3CaKV0SnlW/pfcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}