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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d8c2654c25cb4b641e5b5b2067ca07d0afb2939e3c2578a41857f11cdf80a8d' 
  AND token = 'VcCz+YxvS5yFmudpX61Nv07Ao7lBsKUePdgkts1zuBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}