SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3503c8e2aa8d4e1cc8a5d5874986f2bed8adf63f25b826208819e9f063fe4235' 
  AND token = 'TVaEkvxikW7/3SF/+z9OheYC9yFlziFHB7kaT90mc+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}