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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86cff3bfada9a81c4d544602aa8667999ca84730e27d6d9d455fbeee9f9ce8a0' 
  AND token = 'BGJ03wl9uOk7SOkR1wdyLrtirbWhvTEMU+3qgSMKZnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}