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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0562fe007a4b4198ab2cac9c573772d8e3c470f6a99e9373d9a8c76580114295' 
  AND token = '06K5MxS9CNj58eP2imz3qP6EYXhfkiZ12xCwLjvyeFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}