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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fa4488cb671f61268241c17c33e2fa7ff399bbbc69e7f4b8ad31672eb645f61' 
  AND token = 'rwFyu0sdOkg5aMRaN3bgF1IDO2C1AQxMnGgbdrQvKrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}