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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ca7730164e2fe2ed3b021f5842ba45b496c301a06e707e0786ff4e2cabefd53' 
  AND token = 'mD8lH6O4aQL4Z5u0dXT2R5fuwgCop/O/ZBI8LXETpHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}