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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6b8d71b906a0ded805ec65b8d53d7c0730d0f739680221018c8f05ec5083117' 
  AND token = '8QJ7i57LWHcgoZt0STXDBiAdJAo81HgnkkH6/qtcZ94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}