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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75356b42fc9dd377d81063d4c5c77af510c6c7fa29bdc2d8a21ffed8a36c7743' 
  AND token = 'tgRjR3ZiIPdHyIdP32rQ0NpO5TOR372cHi/SOzyWXHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}