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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b41be61a4f61f4fd4fcee8c9565e39a921d20f98cb212a5239196cfdb1682bf9' 
  AND token = 'MuLxeHc0Bwn6sWGfZLiU40oy1jyXP89BQHujhZqRHnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}