SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f404e16b09a74b4f38834fca6c325ddaff6aa84397edd93c49c00450fe09bc6e' 
  AND token = 'gyIHsfh+6vlws0x4bIl+v2HlO1wdD4SB2EUDDp53RCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}