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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9b873dffce52f3748e2582c748a002edd5b82d61e157420f39297c8fc352a12' 
  AND token = 'uu0zvSSkYhp5AVCwRpmwu2TkfUXhHP5n7hS7+prsv6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}