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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3625b33895f214e6e00f5c0d23d4e8dd654b747480052ab43eb68434f8f6448' 
  AND token = 'm91z+FoSFdLW69QcuozngkNhQ/89ytZJPFw1eYczKn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}