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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cd86b5088cf29eb7d55db3099036e8c888c1bb5835eabe65c301422d0679210' 
  AND token = 'KGwBrS8s+sOWh9tmQ46Pw9pxDe8slIC5u4+j98zoqAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}