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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72daa21b2850489bda442da7d399f3fd87921915e9283e6b7726642081408be6' 
  AND token = 'mbY2kMHCH81fUAr/sq2fOlzfirPQ6xXaOY9GurFX+9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}