SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8caccba2f6bdee0400533d5f7fef567045d2f17cbf45b9b2f5a2b81e6fa0bb6f' 
  AND token = '4Ui8z9MzI4yt2Fl915zuZI2iOjHtLF3YbYcp7fxODA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}