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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bf6b62c8835477270e10d5b508582e26c64dd0429278b514d14fcd69e374e8f' 
  AND token = 'nDXT2xbUnERexeDs0wa60KZ7gb9vMpcDJ3lLDjYRt5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}